Before 1978, Gilgit-Baltistan was cut off from the rest of Pakistan and the world due to the harsh terrain and the lack of accessible roads. All of the roads to the south opened toward the Pakistan-administered state of Azad Kashmir and to the southeast toward the present-day Indian-administered Jammu and Kashmir. During the summer, people could walk across the mountain passes to travel to Rawalpindi. The fastest way to travel was by air, but air travel was accessible only to a few privileged local people and to the Pakistani military and civilian officials. Then, with the assistance of the Chinese government, Pakistan began construction of the Karakoram Highway (KKH), which was completed in 1978. The journey from Rawalpindi / Islamabad to Gilgit takes approximately 20 to 24 hours.
The Karakoram Highway connects Islamabad to Gilgit and Skardu, which are the two major hubs for mountaineering expeditions in Gilgit-Baltistan. Northern Areas Transport Corporation (NATCO) offers bus and jeep transport service to the two hubs and several other popular destinations, lakes, and glaciers in the area. Landslides on the Karakoram Highway are very common. The Karakoram Highway connects Gilgit to Tashkurgan Town, Kashgar, China via Sust, the customs and health-inspection post on the Gilgit-Baltistan side, and the Khunjerab Pass, the highest paved international border crossing in the world at 4,693 metres (15,397 ft).